No matter how sad it sounds, despite being incredibly tech-savvy, modern society is also more prone to various health issues. Statistics showcase an alarming rise in degenerative diseases such as Alzheimer’s and diabetes, especially in aging people.
The degenerative disease results in cell/tissue deterioration, affecting the central nervous and cardiovascular systems. There are some treatment options and methods for such conditions, but most medications provide low bioavailability and drug resistance, poor solubility, and the inability to overpass the blood-brain barrier. Besides, traditional therapeutic tactics are already outdated, so Alzheimer’s disease treatment and diabetes treatment require a completely new approach. Here nanotechnology comes into play.
With the application of these new treatments, quicker drug absorption, aimed interaction at a specific point, and controlled release into the human body will stand possible. So our core task for today is to review how nanomedicines enhance chronic disease treatment like AD and diabetes in-depth.
Benefits of Nanotechnology to AD Therapy
The key accessible treatment option for AD is reducing symptoms via drug limitation to cross the blood-body barrier. So nanotechnology cure strategy offers great potential to eliminate such a limitation due to the benefits below:
- Nanotechnology Immunotherapy
One of the most significant standard immunotherapy drawbacks is preventing immune system-mediated tumor removal owing to the tumor malignancy progression with the following patient’s immune suppression. Plus, modified T-cells might be unsafe for human application to some extent. That’s why nanoparticles appear perfect alternative. They are capable of handling these limitations, increasing the chances of immunotherapy success by turning it secure and efficient.
- Early-Stage Disease Diagnostics
Not only do specialists use nanotechnology knowledge for the advanced treatment of degenerative diseases, but also for getting a clear medical diagnosis vision. For example, iron oxide nanoparticles may significantly improve spectroscopy image contrast. Moreover, the unity of NPs and certain biomarkers allow the discovery of specific tumor phenotypes through ultrasound.
- Biosensors Application
State-of-the-art biosensors contain such nanomaterials as gold NPs, photonic crystals, graphene, and carbon nanotubes because of the demand for high selectivity and sensitivity, and fast detection. In addition, nanotech incorporation into biosensor performance has gifted a vast array of signal transmission enhancements. Launching tools and practices to quantify and image objects at a nanoscale level has promoted the development of biosensors interacting with tiny molecules.
Nanotechnology for Diabetes Management
Within up-to-the-minute nanotech treatment for chronic diseases, diabetes therapy heads the list. Being a widely spread health issue both among youth and older individuals, it just strives for effective nanomedicine solutions.
- Oral Insulin
Since orally delivered insulin is of limited efficiency, the standard insulin hit occurs by injections. The bad news is that it interacts with stomach acid, and due to its vast size, absorption is slow going. It means enzymes in the intestine are likely to digest the insulin partially before the body can soak it up. In this case, there is only little benefit to disease facilitation. Therefore, patients can’t do without nanotechnology to fight diabetes successfully and recover.
Doctors found that chitosan NPs are the best nanomedicines owing to their carrier properties for oral insulin intake. Thus digestive juices can’t ruin insulin, preventing it from getting into the bloodstream.
- Tracking Glucose Level
The hottest medical innovation related to diabetes is nanosensors glucose concentration measurement. Nanotube functioning lets glucose presence change the current streaming down these tubes. Then received data moves to the embedded microchip wirelessly, sending the info to a wearable computer. Hence, unlike ordinary methods, it will help keep abreast of glucose levels in the blood permanently. And the patient can take measures on time to avoid undesired harmful consequences.
